Cerebral palsy
Definition
Cerebral palsy is a group of disorders characterized by loss of movement or loss of other nerve functions. These disorders are caused by injuries to the brain that occur during fetal development or near the time of birth.
Causes, incidence, and risk factors
Cerebral palsy is caused by injury to the cerebrum (the largest portion of the brain, which is involved with higher mental faculties, sensations, and voluntary muscle activities).
Initially cerebral palsy was thought to be related to birth asphyxia (strangulation during birth, which leads to lack of oxygen to the brain) and trauma, but in a study of 45,000 births it was shown that birth asphyxia is an uncommon cause of cerebral palsy. Affected brain areas receive lower levels of oxygen (hypoxia) at some point, but it is not known why this occurs.
Researchers suspect that certain factors or events during the development of the fetus may make it more susceptible to any hypoxia that occurs, and this may be why some infants are affected while others can suffer low oxygen levels but not lasting brain damage.
Premature infants have a slightly higher incidence of cerebral palsy. Cerebral palsy may also occur during early infancy as a result of illnesses (encephalitis, meningitis, herpes simplex infections, and so on), head injury that results in subdural hematoma, blood vessel injuries, and many others.
Injury to the cerebrum can result in the loss of nerve functions in widely different areas. The classical finding of CP is spasticity (increased muscle tone) which may affect a single limb, one side of the body (spastic hemiplegia), both legs (spastic diplegia) or both arms and legs (spastic quadriplegia). In addition, there may be partial or full loss of movement (paralysis), sensory abnormalities, and defects of hearing and vision. Speech abnormalities are common and seizures may occur.
Intellectual function may range from extremely bright normal to severe mental retardation.
